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ALS, Denali

ALS drugs from Denali, Calico come up short, marking setback for Healey trial

Denali’s medicine and a similar one from Calico Life Sciences and AbbVie were not much different than a placebo, bringing the tally of failed drugs in the innovative “Healey platform trial” to seven.

MarketWatch · 2d

Denali Therapeutics Says ALS Trial Didn't Meet Endpoints

Denali Therapeutics said the latest trial of its treatment for amyotrophic lateral sclerosis, or ALS, didn't meet its primary or secondary endpoints after 24 weeks.

Denali Therapeutics' ALS drug fails in mid-to-late stage trial

Denali Therapeutics said on Monday its experimental drug failed to meet the main goal of a mid-to-late stage trial involving patients with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease.

Business Insider · 2d

Denali Therapeutics announces HEALEY ALS trial regimen misses endpoints

Denali Therapeutics (DNLI) announced topline results from an analysis of Regimen G of the Phase 2/3 HEALEY ALS Platform Trial evaluating eIF2B

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Denali Fault Mystery Unveiled: A Geological Breakthrough Reshapes North America’s History

A 620-mile geological enigma that has baffled scientists for decades has finally been solved. The Denali Fault, a massive ...

Denali Therapeutics spinout raises $200M as neuro company resets

Tenvie Therapeutics is making hay from an R&D shift at Denali Therapeutics, acquiring several of its neuroscience drug ...

2d

Denali Therapeutics: Strategic Pipeline Potential and Investment Opportunity Amid Recent Setbacks

Analyst Mayank Mamtani from B.Riley Financial reiterated a Buy rating on Denali Therapeutics (DNLI – Research Report) and keeping the price ...

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Denali Therapeutics’ ALS therapy fails to meet primary endpoint in Phase II/III trial

The primary analysis included 186 subjects who received the therapy and 139 subjects who were given a placebo.

Denali Suffers Another ALS Fail With Phase II/III Flop

Denali’s failure on Monday continues biopharma’s losing streak against amyotrophic lateral sclerosis. PTC Therapeutics and ...

2d

GMC Celebrates 25 Years Of The Denali

To commemorate the 25th anniversary of Denali, GMC is offering customers a special 25th Anniversary Denali Package available ...

Holland America Line to enhance Denali Lodge and Alaska Cruisetours

Stay connected with TTG Media's Noticeboard – your go-to space for industry updates, announcements, and community news from ...

Tenvie Debuts With Denali Assets, $200M for Neurological, Metabolic Diseases

Backed by ARCH Venture Partners, F-Prime Capital and Mubadala Capital, the new company will develop a pipeline of ...

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