The San Francisco 49ers looked at some quarterback options this week as they deal with injury issues for both Brock Purdy and Mac Jones.

The San Francisco 49ers may have to start Adrian Martinez at quarterback this week, so defensive coordinator Robert Saleh shared some info about him.

Asked about Robert Saleh in a fight, 49ers' Kyle Shanahan quipped about Dan Campbell being the one NFL coach that could take him down.

The Detroit Lions and San Francisco 49ers have been named possible trade partners for an elite 79-sack edge rusher who has a slim chance of being available at the trade deadline.

Mac Jones' status for 49ers-Buccaneers in question after injury report originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. The quarterbacks have had a rough go of it to start the 2025 season.

San Francisco 49ers linebacker Fred Warner appeared on the "Manningcast" on Monday, and he dropped a hilarious line about Lions coach Dan Campbell.

The 49ers have signed DL Bruce Hector to the team’s practice squad. In order to make room on the practice squad, the team released S Jaylen Mahoney.

The 49ers ruled out Brock Purdy for the fourth time this season and plan to have Mac Jones start Sunday’s visit to Tampa Bay.

How do all 32 teams in the NFL stack up against each other coming out of Week 5 of the 2025 NFL regular season? Here's an updated look from best to worst.