B cells are a crucial component of immunity, but their function, especially antibody secretion, has largely been studied in the context of secondary lymphoid organs (SLOs) and systemic immune ...

Immune responses and self-tolerance are critical in maintaining systemic and tissue homeostasis. Autoimmune disease results from uncontrolled immune responses against self-antigens, whereas cancer ...

A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific infections, remember them, and mount a targeted response by producing ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

Stage 4 diffuse large B-cell lymphoma (DLBCL) is a rapidly growing lymphoma affecting at least one other organ outside the lymphatic system. Cancer is the unusual growth and spread of cells within the ...

Primary mediastinal B-cell lymphoma (PMBCL) is a rare and aggressive type of non-Hodgkin’s lymphoma that originates in the white blood cells behind the breastbone. Although the cause of PMBCL is ...