Immunotherapies – treatments that aim to make the body's natural immune system more effective – are becoming more widely used ...
Scientists have uncovered how CD4+ T cells can target cancer cells that evade CD8+ T cells, challenging long-held views and ...
New research from the Snow Center for Immune Health is challenging long-held assumptions about autoimmune disease, revealing ...
A novel immune-cell tracking method revealed consistent defects in T-cell function linked to celiac disease. The findings ...
For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...
New research from the Snow Centre for Immune Health is challenging long-held assumptions about autoimmune disease, revealing coeliac disease may be driven not just by an overactive immune system but ...
T cell exhaustion has been implicated in cancer and infectious diseases. In this study, we report a novel mouse model, “MolT-II”, with T cells expressing a transgenic T cell receptor (TCR) specific ...
Immunologists have identified a previously unrecognized group of immune cells that could reshape how vaccines and immune-based therapies are designed. The newly described cells 1 are long-lived memory ...