A new review published in EXO – Beyond the Cell (EXO) examines growing evidence that ferroptosis, an iron-dependent form of ...

Cellular death is a fundamental concept in the biological sciences. Given its significance, its definition depends on the context in which it takes place, and lacks a general mathematical definition.

Cellular sensitivity to cell death stimuli depends on cell-size-dependent proteome changes - specifically, cell size can modulate ferroptosis susceptibility through changes in glutathione biosynthetic ...

Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the ...

There’s a thin line between the living and the dead, and for cells, it depends on whether chemical processes which shut down can be returned to their active states. Cellular death is a fundamental ...

Some go gently into the night. Others die less prettily in freak accidents or deadly invasions, or after a showy display. By Amber Dance/Knowable Magazine Published Sep 27, 2024 8:00 AM EDT This ...

KRAS‑mutant pancreatic cancer relies on caspase‑8 to evade necroptosis, according to a new study in preclinical models.

In an extensive review, researchers explore ZBP1-mediated programmed cell death and its potential as a therapeutic target for systemic diseases Programmed cell death, or PCD, is an actively regulated ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...