Today's nearly $70 billion U.S. biofuels economy is powered by two technology toolboxes. Biochemical technologies—used to produce around 17 billion gallons of ethanol annually—leverage microorganisms ...

Oxidoreductases are key enzymes in biocatalysis, but their dependence on the cofactor nicotinamide adenine dinucleotide (phosphate) (NAD(P)) presents challenges due to its high consumption and ...

Scientists have used microorganisms to produce beneficial chemicals for decades. By providing the microbes with enzymes and metabolic pathways, researchers can coax cells to churn out everything from ...

Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is ...

Transcriptomics, molecular docking and metabolic modelling identify YALI0_F02013g and YALI0_A19910g as NADPH-dependent ...

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same ...

Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, ...

Molecular docking and laboratory validation show bacterial azoreductases decolorize azo and anthraquinone dyes at up to 2,000 ...

This article predates the current owners of Science Blog. It has not been reviewed under the current editorial process and is kept as part of the archive. How Custom-Built Enzymes Were Designed for a ...