Complement Factor H (CFH) is a pivotal regulator of the complement system, integral to maintaining immune homeostasis and protecting host tissues from undue complement‐mediated damage. By inhibiting ...
From this core mechanism Fc engineering has evolved over time into the "engine" of therapeutic antibody development. It ...
A new study offers hope for brain cancer patients facing memory loss from radiotherapy. By blocking a single immune receptor, ...
The deal gives Novo rights to a drug it sees as having "multiple advantages" over other treatments for so-called ...
Neil Bressler, M.D., a professor of ophthalmology at Johns Hopkins and editor-in-chief of JAMA Ophthalmology, argued that complement inhibition for geographic atrophy is a game changer. His debating ...
Nanomedicine uses ultra-small particles to deliver drugs directly to the tissues and cells that need them, improving ...
Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...
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