Researchers at Kanazawa University and the National Institute of Genetics in Japan have used high-speed atomic force ...

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

King’s College London neuroscientists report that KCL-286, an experimental pill first developed for spinal cord injuries, ...

DNA damage is associated with aging and premature aging disorders. Here, the authors show that small molecule activation of the kinesin-13 KIF2C improves double-strand break DNA repair in aged cells ...

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

St. Jude researchers show the DNA repair enzyme PARP1 evicts two histones near damage sites, forming hexasomes that recruit ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

T ing Zhao, an assistant professor of molecular, cell, and systems biology at UC Riverside, has received a K01 Career Development Award from the National Institute on Aging (NIA) to investigate how ...

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging. Researchers at ...