Across contemporary cardiovascular clinical trials, the estimates of expected event rates and effect sizes that investigators use to calculate sample sizes—and funding requirements—often come in ...

Accurate and efficient classification of variant pathogenicity is critical for research and clinical care. Using data from three large studies, we demonstrate that population-based associations ...

Many researchers rely on meta-analysis to summarize research evidence. However, there is a concern that publication bias and selective reporting may lead to biased meta-analytic effect sizes. We ...

Basic concepts in hypothesis testing, including effect sizes, type I and type II errors, calculation of statistical power, non-centrality parameter, and applications of these concepts to twin studies.

Standard effect sizes are more meaningful outcomes in Alzheimer's disease drug trials than the widely used metric of percent slowing of decline, an analysis suggested. In recent trials of Alzheimer's ...

Please provide your email address to receive an email when new articles are posted on . Differences between individuals with autism and those without have lessened over time, which may be tied to ...