Researchers from the University College London have brought us one step closer to understanding how we feel pain. Their study, published in Brain, describes a rare genetic mutation found in a patient ...

The research and development arm of Janssen Pharmaceuticals, a Johnson & Johnson company, announced on Sunday (January 17) their voluntary suspension of dosing in two Phase 2 clinical trials of their ...

Chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH). The enzyme has been considered for treatment for cannabis dependence because it breaks down substances ...

A new research paper titled "FAAH inhibition ameliorates breast cancer in a murine model" has been published in Oncotarget. Breast cancer is the leading cancer among females worldwide. Disease outcome ...

Fatty acid amide hydrolase (FAAH) is the main degrading enzyme of the fatty acid ethanolamides anandamide (AEA) and oleoylethanolamide (OEA), which have opposite effects on food intake and energy ...

A Scottish woman who feels virtually no pain has left British researchers not only astounded but looking for a way to harness her previously unidentified genetic mutation to guide new treatments for a ...

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from ...

A Scottish woman in her 70s has lived a life without pain and fear. New research pinpoints unique mutations in her DNA. Reading time 3 minutes Scientists are starting to crack the mystery behind one ...

A woman in Scotland can feel virtually no pain due to a mutation in a previously-unidentified gene, according to a research article. She also experiences very little anxiety and fear, and may have ...

Figure 1: An overview of the endocannabinoid pathway and molecules tested in this study. “This study explores the functional relevance and therapeutic potential of FAAH inhibition combined with the ...