Immunome Inc. IMNM said the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application for varegacestat, ...

FDA NDA acceptance for varegacestat positions it as a potential second oral targeted option for progressing desmoid tumors, ...

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's ...

June 15, 2007 (Washington, DC) — A drug that deactivates gamma-secretase, an enzyme involved in amyloid-beta (Abeta) synthesis, appears to be safe and reduces plasma concentrations of Abeta in ...

Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational ...

New research has uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease. In a first step, two dimeric ...

Based on structural similarities with other targets of the gamma-secretase system, researchers from Columbia University Irving Medical Center in the United States show that the SARS-CoV-2 receptor for ...

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's ...

From the Damian Green Lab, in collaboration with the Geoff Hill and Riddell Labs, Translational Sciences and Therapeutics Division and David Coffey, Division of Myeloma, at the University of Miami To ...

Intensity-modulated radiation therapy for pediatric head and neck rhabdomyosarcoma: French preliminary results. Late side effects of neoadjuvant chemotherapy in patients treated for osteosarcoma and ...