A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

Chemical-genetic interaction profiling harnesses the genetic tractability of fungal models to map systematically how small molecules perturb cellular networks. By exposing collections of gene deletion ...

Aquaporin-4 genetic variants interact with short sleep to accelerate grey matter loss linked to early Alzheimer's disease.

Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in ...

There are individuals who carry the same deletion of chromosome 16, and those same delections can lead to a wide range of potential neurodevelopmental issues in carriers, from milder mental illnesses ...

A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions between human and viral genomes shape disease risk. The research found that ...

Filamentous fungi exhibit a remarkable capacity to coordinate genetic activity across expansive, multinucleate networks of hyphae. Genetic interactions in these organisms encompass heterokaryosis—the ...

A new study indicates a common genetic variant may interact with gut bacteria to trigger chronic inflammation in ulcerative colitis. The findings may help explain why people experience the disease ...

National University of Singapore, Yong Loo Lin School of Medicine Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today - knowing a gene ...

When two homozygous plant lines with different characteristics are crossed, the resulting offspring are often more robust and productive than their parents. This phenomenon is called heterosis. It can ...

This study is led by Professors Huihui Li (Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China), Liang Li (Institute of Crop Sciences, Chinese Academy of Agricultural ...