Scientists have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in 'filtering' sensory information. The new research demonstrates ...

A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

Researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (TX, USA) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Loss of synapses and synapse function sit at the heart of a number of diseases, not just neurodegenerative examples such as dementia and Parkinson's disease but also conditions such as diabetes. We do ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Real neurons don't actually talk to each other with electrical spikes. For that, their synapses deploy vesicles filled with transmitters. Although there is clearly a relation between the spikes a ...

Synapse labeling strategies involve marking synaptic contact sites with different fluorescent proteins in the pre- and postsynaptic compartments. The interface between these contacts is also labeled, ...

Scientists at Yale and the University of Connecticut have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in “filtering” sensory ...