Spinal cord injuries cause permanent paralysis in part because inflammation, cell death, and glial scarring block nerve regeneration, and there has been no reliable human tissue model to test ...

The spinal cord plays critical roles in the neurotransmission of sensory inputs and motor outputs between the brain and the body, coordination of central pattern generation, and many sensorimotor ...

Organoids modeled on the structure of the human spinal cord have been shown to match the behavior of an injured spine. Now, a treatment that has worked well in mice has been applied to the organoids, ...

Damage to the spinal cord can lead to irreversible paralysis and loss of sensory function, but translation of preclinical therapies remains elusive. We recently showed that bioactive supramolecular ...

Researchers have built a realistic human mini spinal cord in the lab and used it to simulate traumatic injury. The model reproduced key damage seen in real spinal cord injuries, including inflammation ...

Northwestern University (IL, USA) scientists have developed the most advanced organoid model for human spinal cord injury to date. In a new study, the research team used lab-grown human spinal cord ...

Fluorescent micrographs showing increased neurite outgrowth from a human spinal cord organoid treated with fast-moving “dancing molecules” (left) compared to one treated with slow-moving molecules ...