Noxa is a proapoptotic BH3-only member of the Bcl-2 family, which binds specifically Mcl-1 (see Willis and Adam 6 for review). When its BH3 domain inserts within the hydrophobic groove of Mcl-1, this ...

The formation of amyloid-β peptide (Aβ) fibrils in areas of the brain related to memory is an important event in the development of Alzheimer's disease. Studies in rodents have suggested that ...

A study challenges the efficacy of the once-hallowed herbal supplement St. John's wort utility as an antidepressant. Hypericin, hyperforin. SHARE A recent study challenges the efficacy of the ...

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