The Pittsburgh Steelers will look to build on their lead in the AFC North when they take on the visiting Cleveland Browns in a key Week 6 matchup. The Steelers enter with a 3-1 mark, while the 1-4 Browns will be out to snap a two-game losing streak,

Week 6 of the NFL season is set to begin tonight so it's time to lock in your pick'em pool plays and you spread bets for this weekend's action. Only the Houston

The league's latest round of games begins with a heated NFC East rivalry and ends with yet another Monday night doubleheader.

Pete Prisco reveals all of his Week 6 picks, including Trevor Lawrence and the Jaguars outscoring Sam Darnold and the Seahawks

The Bengals and Ravens are both missing their quarterbacks, but so are the 49ers. It could get worse for Cincy and Baltimore this week.

The line is moving toward the Chiefs, likely because the Lions secondary is in shambles. Cornerbacks Terrion Arnold and D.J. Reed are set to miss time due to injuries. The Chiefs might have lost on Monday night, but Patrick Mahomes was fantastic. The combination of the Lions' injuries and the Chiefs' desperation lead to a pick for Kansas City.

Also, let's not ignore the tremendous season that Sam Darnold is putting together for the Seahawks. Remarkably, his completion percentage and passer rating are even better than what he produced last season with the Vikings. I think he leads Seattle into Duval County and leaves with an outright win.