A new collaborative study shows how blood vessel genes play a critical role in motor neuron development by telling blood vessels to get out of the way. The discovery has implications for understanding ...

The prefrontal cortex (PFC) is a crucial part of the mammalian brain, known to be involved in decision-making, planning, complex social behavior and integrating the activity of other brain regions.

A progenitor-derived corticospinal-like neuron in cell culture, extending its long axon, even in isolation. The cell body (or "soma"; immunolabeled by Tuj1 antibody in red) is at the top, with the ...

Cambridge researchers created miniature brain-and-spinal-cord systems in the lab that can send signals and even trigger tiny muscle contractions. They discovered that human neurons gradually lose ...

Modern medicine can do a lot of amazing things. But if the nerve cables linking the human brain and spinal cord are severed, ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, ...

Cambridge scientists have grown miniature circuits in the lab that mimic how the brain and spinal cord connect up, which underlies our movements. They used this model to show how damage to these ...

After a spinal-cord injury, adult nerve cells do something frustrating: they hunker down and survive, but they refuse to regrow. For decades, scientists have tried to coax those neurons back into ...

To allow for the local translation of proteins that suit the ever-changing needs of the axon, neurons must ship transcripts from the soma to their outermost reaches. For thousands of these mRNAs, ...

During the assembly of the nervous system, neurons extend axons over long distances to reach appropriate targets and form functional circuits. This process is guided by growth cones—dynamic structures ...