Nicotine has a half-life of about two hours and can stay in the blood for about one to three days. Cotinine, a byproduct of nicotine, has a half-life of 18 hours and can last for several days.

Nicotine withdrawal induces behavioral symptoms such as tremors and shaking. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine significantly reduces ...

After a free, evidence-based guide to health and wellness? Sign up to our weekly Well Informed newsletter. BY SOME reckonings, nicotine is as addictive as cocaine. It has led legions to a slow death ...

Nicotine quickly enters your bloodstream. Your liver then breaks down nicotine into several byproducts, primarily cotinine. Depending on what you're testing, such as a blood, urine, saliva, or hair ...