Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

During osteoclast differentiation, Ctdnep1 expression remains consistent, yet its depletion results in heightened osteoclast formation and activity. Mechanistically, Ctdnep1 demonstrates a suppressive ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...