Endothelin signalling in vascular smooth muscle constitutes a central mechanism by which the endothelium regulates vascular tone, structure and remodelling. The 21-amino-acid peptide endothelin-1 ...
A recent study by University Medicine Halle shows how sepsis can lead to dysfunction of vascular smooth muscle cells. The researchers found that elevated lactate levels and acidosis, which can occur ...
Vascular aging is a complex pathophysiological process propelled by endothelial dysfunction, oxidative stress, chronic inflammation, cellular senescence, endothelial stiffening, and vascular smooth ...
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