The San Francisco 49ers have officially ruled out left tackle Trent Williams for the remainder of the season after he missed ...

The San Francisco 49ers have signed offensive lineman Charlie Heck to a one-year deal and placed offensive lineman Jaylon ...

The 49ers are one of the worst teams in the NFL this season. This past week, they got run over by the Miami Dolphins, who are ...

Currently, the 49ers are slotted to draft 11th in Round 1. And CBS's Ryan Wilson expects them to take Ohio State offensive ...

The San Francisco 49ers return to Levi's Stadium to host the Detroit Lions on ESPN's Monday Night Football. This matchup ...

The Miami Dolphins will host the San Francisco 49ers at Hard Rock Stadium in Miami Gardens, Florida, on Sunday, December 22, ...

The San Francisco 49ers have officially ruled out left tackle Trent Williams for the remainder of the season after he missed five consecutive games. Jaylon Moore, who has been filling in for Williams, ...

Detroit Lions head coach Dan Campbell has no plans to hold back on Monday night against the San Francisco 49ers—the team that dashed their Super Bowl ...

Defensive end Yetur Gross-Matos is in his first season with the San Francisco 49ers, having signed as a free agent with hopes ...

San Francisco 49ers quarterback Brock Purdy has been sacked six times over the past two games, and his protection won't be ...

A week and a half after Dre Greenlaw made his season debut, it seems his season ended. Greenlaw left Sunday's loss to the ...

San Francisco 49ers head coach Kyle Shanahan provided key injury updates ahead of Wednesday's practice as the team prepares ...