Actor Eric Dane, best known for playing Dr. Mark "McSteamy" Sloan in Grey's Anatomy, is opening up about his battle with Amyotrophic Lateral Sclerosis (ALS) disease, revealing in a recent interview that he has lost control of his right arm.

Nevertheless, Dane remains hopeful. “I’m fighting as much as I can,” Dane said. “There’s so much about it that’s out of my control.” Later, he added, “In my heart I don’t feel like this is the end of me.”

Eric Dane detailed the heartbreaking effects that ALS has had on his body just two months after the Grey’s Anatomy alum shared his diagnosis with the world.