Medically reviewed by Mary Choy, PharmD Key Takeaways Nicotine has a half-life of about two hours and can stay in the blood for about one to three days. Cotinine, a byproduct of nicotine, has a ...

A new study shows that abstinent smokers experience heightened pain sensitivity linked to altered activity in specific brain ...

Nicotine withdrawal induces behavioral symptoms such as tremors and shaking. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine significantly reduces ...

Has nicotine addiction finally met its match? Smoking is one of the most harmful habits to adopt because it can cause lung cancer, heart disease and several other dire health problems. Nevertheless, ...

Abstinent smokers experience increased pain sensitivity during withdrawal, to the point that they often require more pain ...

Nicotine & Tobacco Research, Vol. 15, No. 11 (November 2013), pp. 1849-1857 (9 pages) Introduction: Concerns exist that varenicline may cause neuropsychiatric side effects. Some of these symptoms (e.g ...

If you are quitting smoking, you may develop symptoms like coughing and fatigue, called "smoker's flu." Nicotine replacement therapy can ease smoker's flu and other withdrawal symptoms. You can try ...

Because unpleasant withdrawal symptoms fuel nicotine addiction's high relapse rate, targeting their underlying mechanisms with treatments may promote continued abstinence from the drug. In a new ...

Alabama Barker, 19, daughter of Blink-182 drummer Travis Barker, was rushed to the hospital after experiencing severe nicotine withdrawal symptoms following her decision to quit vaping cold turkey.