1Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, Washington. 2Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.

Abstract. In recent years, accumulation of mitochondrial reactive oxygen species (ROS) has been shown to limit the proliferative capacity and intratumoral persistence of CD8+ T cells, but the ...

Department of Physiology, University of Kentucky Schoof of Medicine, Lexington, Kentucky. *Corresponding Author: Erhard Bieberich, Department of Physiology, University of Kentucky College of Medicine, ...

1The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2The Lung Cancer Precision Medicine Center of Excellence, Johns Hopkins University ...

2Department of Surgery, The University of Michigan Medical School, Ann Arbor, Michigan. 3Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan. 4Department of Cell and Developmental Biology ...

Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

1Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Broad Institute of Harvard and MIT, Cambridge, ...

*Corresponding Author: Anne McTiernan, Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Avenue North, P.O. Box 19024, Seattle, WA 98109. E-mail: [email protected] ...

Creighton University School of Medicine, Omaha, NE.

Anwita Biosciences, San Carlos, CA.

University of Arkansas for Medical Sciences, Little Rock, AR.

Abstract. We investigated the effect of small molecules extracted from the latex of Calotropis procera (CPPE) to act as inhibitors of Heat Shock Protein 90 (HSP90), a key molecular chaperone co-opted ...