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As second-line therapy for PsA and axSpA, no clear treatment-retention benefit at 3 years was seen when swapping to a bDMARD with another MOA.
In moderate to severe Crohn's disease, a network meta-analysis suggested that TNF inhibitor-based therapy was the most ...
Large cohort study finds TNF inhibitors linked to lower cancer risk in psoriasis, supporting long-term safety of biologic ...
Tumor necrosis factor inhibitor use in patients with IMIDs did not increase the risk of de novo heart failure or worsen existing heart failure.
Tapering TNF inhibitors is safe and maintains low disease activity for 2 years in psoriatic arthritis and axial ...
Juvenile idiopathic arthritis, older age, and concomitant immunomodulation delay the onset of psoriasiform dermatitis in ...
The Crohn’s disease (CD) treatment landscape is undergoing a radical transformation as newer mechanisms of action (MOAs), particularly IL-23 inhibitors and JAK ...
A growing number of women with chronic inflammatory diseases are continuing to use TNF inhibitors throughout pregnancy.
Observational data in inflammatory bowel disease (IBD) supported the safety of JAK inhibitors versus TNF inhibitors in terms of serious outcomes -- including blood clots, major heart events, and ...
Observational data in inflammatory bowel disease (IBD) supported the safety of JAK inhibitors versus TNF inhibitors in terms of serious outcomes -- including blood clots, major heart events, and ...