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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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Las infecciones respiratorias siguen bajo vigilancia en Bogotá y la ocupación hospitalaria supera el 90 % en adultos, mientras que en pediatría llega al 89,4 %. Entre los virus identificados están el sincitial respiratorio, que puede causar complicaciones en niños pequeños, y la influenza, que puede provocar fiebre, dolores musculares y complicaciones graves en personas vulnerables. Las autoridades recomiendan mantener las vacunas al día, ventilar los espacios y consultar ante señales de alarma.
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