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USMLE High-Yield Questions on Instagram: "Mood stabilized. Bladder destabilized 😭💀 ⸻ ✅ Explanation (with answer) Correct answer: C) Nephrogenic diabetes insipidus Lithium causes nephrogenic DI by making the kidneys unresponsive to ADH at the collecting ducts. Key clues: • Polyuria + polydipsia • On lithium • Normal glucose (rules out osmotic diuresis) Lithium interferes with ADH signaling → inability to concentrate urine → excessive dilute urine output. High-yield: persistent cases can be trea
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